Cell Biology Recombinant Proteins
Human CD44 Recombinant Protein (RPES5202)
- SKU:
- RPES5202
Description
Human CD44 Recombinant Protein
CD44 is a cell-surface receptor for hyaluronic acid and also interacts with other ligands; such as osteopontin; collagens; and matrix metalloproteinases. A large number of CD44 isoforms can be generated by the insertion of different combinations of at least nine exons. Increased CD44 antigen is associated with relapses in non-small cell lung cancers. Furthermore; an increasing quantity of evidence suggests that CD44 has various functions related to inflammatory disease. CD44 deficiency induces severe liver injury. CD44-hyaluronate mediates in lymphocyte T and monocyte adhesion to the endothelium; stimulates proinflammatory cytokine release from macrophages and participates in dedifferentiation phenotype of smooth muscle cells from contractile state to synthetic one.
| Product Name: | Human CD44 Recombinant Protein (RPES5202) |
| Product Code: | RPES5202 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | CDW44,CSPG8,ECMR-III,HCELL,HUTCH-I,IN,LHR,MC56,MDU2,MDU3,MIC4,Pgp1, Epican, Extracellular Matrix Receptor III, ECMR-III, GP90 Lymphocyte Homing/Adhesion Receptor, HUTCH-I, Heparan Sulfate Proteoglycan, Hermes Antigen, Hyaluronate Receptor, Phagocytic Glycoprotein 1, PGP-1, Phagocytic Glycoprotein I, PGP-I, CD44 |
| Accession: | P16070 |
| Sequence: | Gln21-Pro220 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human CD44 is produced by our Mammalian expression system and the target gene encoding Gln21-Pro220 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 23.1 kDa |
| AP Mol Mass: | 44 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB; 150mM NaCl; pH 7.2. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Additional Information
Product Type: |
Recombinant Protein |
Species: |
Human |
Research Area: |
Cell Biology |
Related Products
Human CD44 Recombinant Protein (RPES5223)
Cell Biology Recombinant Proteins
Human CD44 Recombinant Protein (RPPB3038)
CD Antigens Recombinant Proteins
Human CD44 Recombinant Protein (His Tag) (HDPT0133)
Immune Checkpoint Recombinant Proteins
