Immune Checkpoint Recombinant Proteins
Human CD43 Recombinant Protein (hFc Tag) (HDPT0476)
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- SKU:
- HDPT0476
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
Description
Human CD43 Recombinant Protein (hFc Tag)
| Description: | This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017] |
| Product name: | Human CD43 Recombinant Protein (hFc Tag) |
| Synonyms: | CD43; GALGP; GPL115; LSN |
| Type: | protein |
| Size: | 50 µg |
| Name: | CD43 |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | Contact Technical Support |
| Purity: | Contact Technical Support |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | C-Human Fc |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | CD43 (Ser20-R253)+hFc(GLU99-ALA330) |
| Gene ID: | |
| Uniprot: | P16150 |
| Molecular Weight: | 51.26 kDa |
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