Description
system_update_altDatasheet
| Antibody Name: | Human CD41 Monoclonal Antibody (Biotin Conjugated) |
| Antibody Code: | AGEL0325 |
| Size: | 100µg |
| Clone: | HIP8 |
| Synonyms: | Integrin alpha-Iib, ITGA2B, GPalpha Iib, GPIIb, Platelet membrane glycoprotein Iib, CD41, GP2B, ITGAB |
| Host Species: | Mouse |
| Species Reactivity: | Human |
| Applications: | FC |
| Concentration: | 1mg/mL |
| Isotype: | IgG1 |
| Conjugation: | Biotin |
| Applications: | FC |
| Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| Storage Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Storage: | Keep as concentrated solution.Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
| Gene ID: | 3674 |
| Uniprot: | P08514 |
| Background: | CD41 is a 125/25 kD α subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbα) and light chain (gpIIbβ) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor and thrombin. |