Description
system_update_altDatasheet
Antibody Name: | Human CD41 Monoclonal Antibody (Biotin Conjugated) |
Antibody Code: | AGEL0325 |
Size: | 100µg |
Clone: | HIP8 |
Synonyms: | Integrin alpha-Iib, ITGA2B, GPalpha Iib, GPIIb, Platelet membrane glycoprotein Iib, CD41, GP2B, ITGAB |
Host Species: | Mouse |
Species Reactivity: | Human |
Applications: | FC |
Concentration: | 1mg/mL |
Isotype: | IgG1 |
Conjugation: | Biotin |
Applications: | FC |
Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Storage Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Storage: | Keep as concentrated solution.Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Gene ID: | 3674 |
Uniprot: | P08514 |
Background: | CD41 is a 125/25 kD α subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbα) and light chain (gpIIbβ) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor and thrombin. |