Growth Factors & Cytokines Recombinant Proteins
Human CD40L/TNFSF5 Recombinant Protein (RPES5163)
- SKU:
- RPES5163
Description
Human CD40L/TNFSF5 Recombinant Protein
CD40 Ligand (CD40LG) is a type II transmembrane glycoprotein from the TNF superfamily. CD40LG exists as a trimer in membrane-bound and soluble form, both of which are bioactive. CD40L is a CD40 ligand that activates signal transduction in CD40LG-expressing cells through ligation. CD40LG is a differentiation antigen that T-cells express on their surface. It stimulates B-cell proliferation and production of all immunoglobulin isotypes in the presence of cytokines. CD40LG has been found to generate and destroy tumour cells in peripheral blood monocytes. It also co-stimulates the proliferation of activated T-cells and this is accompanied by the production of IFN-gamma; TNF-alpha; and IL2. Human CD40L/TNFSF5 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
| Product Name: | Human CD40L/TNFSF5 Recombinant Protein (RPES5163) |
| Product Code: | RPES5163 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | CD40 Ligand, CD40-L, T-Cell Antigen Gp39, TNF-Related Activation Protein, TRAP, Tumor Necrosis Factor Ligand Superfamily Member 5, CD154, CD40LG, CD40L, TNFSF5, TRAP,hCD40L,HIGM1,IGM,IMD3,T-BAM,TNFSF5,TRAP |
| Accession: | P29965 |
| Sequence: | Met 113-Leu261 |
| Fusion tag: | |
| Activity: | Immobilized Human CD40L at 10µg/ml(100 ?l/well) can bind Human CD40-His(Cat: PKSH033723). |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human CD40 Ligand is produced by our Mammalian expression system and the target gene encoding Met113-Leu261 is expressed. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 16.2 kDa |
| AP Mol Mass: | 16-18 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB; 200mM NaCl; 0.1mM EDTA; pH 7.0. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Additional Information
Product Type: |
Recombinant Protein |
Species: |
Human |
Research Area: |
Growth Factors & Cytokines |
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