Description
system_update_altDatasheet
Antibody Name: | Human CD4 Monoclonal Antibody (Biotin Conjugated) |
Antibody Code: | AGEL0398 |
Size: | 100µg |
Clone: | RPA-T4 |
Synonyms: | T-cell surface glycoprotein CD4, CD4, T-cell surface antigen T4/Leu-3, CD4 |
Host Species: | Mouse |
Species Reactivity: | Human |
Applications: | FC |
Concentration: | 1mg/mL |
Isotype: | IgG1 |
Conjugation: | Biotin |
Applications: | FC |
Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Storage Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Storage: | Keep as concentrated solution.Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Gene ID: | 920 |
Uniprot: | P01730 |
Background: | CD4, also known as T4/Leu-3, is a 55 kD single-chain type I transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR/CD3 complex, binds to β2 domain from the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7). |