Description
Antibody Name: | Human CD4 Monoclonal Antibody (AF647 Conjugated) |
Antibody Code: | AGEL1389 |
Size: | 50 Tests |
Clone: | RPA-T4 |
Synonyms: | T-cell surface glycoprotein CD4,CD4,T-cell surface antigen T4/Leu-3,CD4 |
Host Species: | Mouse |
Species Reactivity: | Human |
Applications: | FC |
Concentration: | 5uL |
Isotype: | IgG2a,k |
Conjugation: | AF647 |
Applications: | FC |
Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
Storage Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Storage: | Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. |
Gene ID: | 920 |
Uniprot: | P01730 |
Background: | CD4, also known as T4/Leu-3, is a 55 kD single-chain type I transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR/CD3 complex, binds to β2 domain from the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7). |
Human peripheral blood lymphocytes are stained with Anrti-Human CD4 Monoclonal Antibody(AF647 Conjuaged)(filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control. |