Immune Checkpoint Recombinant Proteins

Human CD38 Recombinant Protein (hFc Tag) (HDPT0177)

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SKU:
HDPT0177
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immune Checkpoint

Description

Human CD38 Recombinant Protein (hFc Tag)

Description:CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.
Product name:Human CD38 Recombinant Protein (hFc Tag)
Synonyms:CD38, T10, cADPr hydrolase 1
Type:protein
Size:50 µg
Name:CD38
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:Contact Technical Support
Purity:> 95%
Purification:affinity purification
Format:Lyophilized
Conjugate:C-Human Fc
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:CD38(Val43-Ile300)+hFc(Glu99-Ala330)
Gene ID:952
Uniprot:P28907
Molecular Weight:70-100 kDa
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