Description
Antibody Name: | Human CD35 Monoclonal Antibody (PE/Cyanine7 Conjugated) |
Antibody Code: | AGEL1014 |
Size: | 50 Tests |
Clone: | E11 |
Synonyms: | Complement receptor type 1,CR1,C3b/C4b receptor,CD35,CR1,C3BR |
Host Species: | Mouse |
Species Reactivity: | Human |
Applications: | FC |
Concentration: | 5uL |
Isotype: | IgG2a,k |
Conjugation: | PE/Cyanine7 |
Applications: | FC |
Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
Storage Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Storage: | Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. |
Gene ID: | 1378 |
Uniprot: | P17927 |
Background: | CD35 is a type I single chain of glycoprotein, also known as C3b/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes, and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. CD35 has also been reported to inhibit T-cell proliferation. |
Human peripheral blood lymphocytes are stained with Anti-Human CD35 Monoclonal Antibody(PE/Cyanine7 Conjugated)(filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control. |