Human CD32 Monoclonal Antibody (PE/Cyanine7 Conjugated) [IV-3](AGEL1077)

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SKU:
AGEL1077
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC

Description

Antibody Name:Human CD32 Monoclonal Antibody (PE/Cyanine7 Conjugated)
Antibody Code:AGEL1077
Size:50 Tests
Clone:IV-3
Synonyms:Low affinity immunoglobulin gamma Fc region receptor II-b,FCGR2B,IgG Fc receptor II-b,CDw32,Fc-gamma RII-b,Fc-gamma-RIIb,FcRII-b,CD32,FCG2, IGFR2
Host Species:Mouse
Species Reactivity:Human
Applications:FC
Concentration:5uL
Isotype:IgG2a,k
Conjugation:PE/Cyanine7
Applications:FC
Recommended Dilution:Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Storage Buffer:PBS with 0.05% Proclin300, 1% BSA
Storage:Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.
Gene ID:2212
Uniprot:P31994
Background:CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).
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