Description
system_update_altDatasheet
Antibody Name: | Human CD29 Monoclonal Antibody |
Antibody Code: | AGEL0212 |
Size: | 100µg |
Clone: | TS2/16.2.1 |
Synonyms: | Integrin beta-1, ITB1, Itgb1, Fibronectin receptor subunit beta, VLA-4 subunit beta, CD29 |
Host Species: | Mouse |
Species Reactivity: | Human |
Applications: | FC, IHC, IF, IP |
Concentration: | 1mg/mL |
Isotype: | IgG1 |
Conjugation: | Unconjugated |
Applications: | FC, IHC, IF, IP |
Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Storage Buffer: | PBS with 0.05% Proclin300 |
Storage: | Keep as concentrated solution.Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Gene ID: | 3688 |
Uniprot: | P05556 |
Background: | CD29 is a 130 kD single chain type I glycoprotein also known as integrin β1, VLA-β chain, or gpIIa. It is broadly expressed on a majority of hematopoietic and non-hematopoietic cells, including leukocytes (although at low level on granulocytes), platelets, fibroblasts, endothelial cells, epithelial cells, and mast cells. CD29 is a member of the integrin family. It is non-covalently associated with integrin α1-α6 chains to form VLA-1 to VLA-6 molecules, respectively. Integrins, which include CD29, bind to several cell surface (e.g. VCAM-1, MadCAM-1) and extracellular matrix molecules. CD29 acts as a fibronectin receptor and is involved in a variety of cell-cell and cell-matrix interactions. |