Human CD274/PD-L1 Monoclonal Antibody (PE Conjugated) [29E.2A3](AGEL1649)

Name: Human CD274/PD-L1 Monoclonal Antibody (PE Conjugated) [29E.2A3](AGEL1649)
SKU: AGEL1649
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OverviewAntibody Name:Human CD274/PD-L1 Monoclonal Antibody (APC Conjugated)Antibody Code:AGEL1650Size:50 TestsClone:29E.2A3

OverviewAntibody Name:Human CD274/PD-L1 Monoclonal Antibody (Biotin Conjugated)Antibody Code:AGEL1647Size:100µgClone:29E.2A3<

OverviewAntibody Name:Human CD274/PD-L1 Monoclonal Antibody (FITC Conjugated)Antibody Code:AGEL1648Size:50 TestsClone:29E.2A3<

OverviewAntibody Name:Purified Human CD274/PD-L1 Monoclonal AntibodyAntibody Code:AGEL1646Size:100µgClone:29E.2A3

OverviewProduct Name:PE/Cyanine7 Anti-Human CD274/PD-L1 Antibody [29E.2A3]Product Code:AGEL2262Clone No:29E.2A3Synonyms:B7-H1, PD

OverviewProduct Name:PE/Cyanine5 Anti-Human CD274/PD-L1 Antibody [29E.2A3]Product Code:AGEL2261Clone No:29E.2A3Synonyms:B7-H1, PD

OverviewAntibody Name:AF/LE Purified Human CD274/PD-L1 Monoclonal AntibodyAntibody Code:AGEL1645Size:500µgClone:29E.2A3<

OverviewProduct Name:PerCP/Cyanine5.5 Anti-Human CD274/PD-L1 Antibody [29E.2A3]Product Code:AGEL2263Clone No:29E.2A3Synonyms:B7-H

OverviewAntibody Name:Mouse CD274/PD-L1 Monoclonal Antibody (PE Conjugated)Antibody Code:AGEL1642Size:50µgClone:10F.9G2<

Concentration:	5uL
Isotype:	IgG2a,k
Conjugation:	PE
Applications:	FC
Recommended Dilution:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Storage Buffer:	PBS with 0.05% Proclin300, 1% BSA
Storage:	Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.

Gene ID:	29126
Uniprot:	Q9NZQ7
Background:	CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.

Antibody Name:	Human CD274/PD-L1 Monoclonal Antibody (PE Conjugated)
Antibody Code:	AGEL1649
Size:	50 Tests
Clone:	29E.2A3
Synonyms:	B7-H1, PD-L1,Programmed cell death ligand 1,B7 homolog 1,B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1
Host Species:	Mouse
Species Reactivity:	Human
Applications:	FC