Immune Checkpoint Recombinant Proteins

Human CD27 Recombinant Protein (mFc-His Tag) (HDPT0013)

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SKU:: HDPT0013
UPC:
MPN:
Product Type:: Recombinant Protein
Species:: Human
Research Area:: Immune Checkpoint

Description
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Description

Human CD27 Recombinant Protein (mFc-His Tag)

Description:	The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Product name:	Human CD27 Recombinant Protein (mFc-His Tag)
Synonyms:	CD27, TNFRSF7, S152, T14, Tp55
Type:	protein
Size:	50 µg
Name:	CD27
Origin:	Human
Source:	HEK293
Protein Type:	Recombinant
Application:	Contact Technical Support
Purity:	> 95%
Purification:	affinity purification
Format:	Lyophilized
Conjugate:	C-Mouse Fc and 6×His tag
Storage:	Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:	Research use only
Buffer:	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:	Reconstitute with deionized water
Sequence:	CD27（Ala20-Arg191）+mFc（Pro99-Lys330）+6×His
Gene ID:	939
Uniprot:	P26842
Molecular Weight:	65-72 kDa

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