Immune Checkpoint Recombinant Proteins

Human CD27 Recombinant Protein (hFc Tag) (HDPT0087)

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SKU:
HDPT0087
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immune Checkpoint

Description

Human CD27 Recombinant Protein (hFc Tag)

Description:The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Product name:Human CD27 Recombinant Protein (hFc Tag)
Synonyms:CD27, TNFRSF7, S152, T14, Tp55
Type:protein
Size:50 µg
Name:CD27
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:ELISA
Purity:> 95%
Purification:affinity purification
Format:Lyophilized
Conjugate:C-Human Fc
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:CD27(Ala20-Arg191)+hFc(Glu99-Ala330)
Gene ID:939
Uniprot:P26842
Molecular Weight:45.3 kDa
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