Immune Checkpoint Recombinant Proteins
Human CD27 Recombinant Protein (hFc Tag) (HDPT0087)
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- SKU:
- HDPT0087
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
Description
Human CD27 Recombinant Protein (hFc Tag)
| Description: | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. |
| Product name: | Human CD27 Recombinant Protein (hFc Tag) |
| Synonyms: | CD27, TNFRSF7, S152, T14, Tp55 |
| Type: | protein |
| Size: | 50 µg |
| Name: | CD27 |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | ELISA |
| Purity: | > 95% |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | C-Human Fc |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | CD27（Ala20-Arg191）+hFc（Glu99-Ala330） |
| Gene ID: | 939 |
| Uniprot: | P26842 |
| Molecular Weight: | 45.3 kDa |
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