CD Antigens Recombinant Proteins

Human CD200 Recombinant Protein (RPPB3109)

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RPPB3109

Description

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Product Name:Human CD200 Recombinant Protein
Product Code:RPPB3109
Size:10µg
Species:Human
Target:CD200
Synonyms:CD200, MOX1, MOX2, MRC, OX-2, CD200 Molecule, CD200 Antigen, Antigen Identified By Monoclonal Antibody MRC OX-2, OX-2 Membrane Glycoprotein.
Source:Sf9 Insect cells
Physical Appearance:Sterile Filtered colorless solution.
Formulation:CD200 protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).�Avoid multiple freeze-thaw cycles.
Purity:Greater than 95.0% as determined by SDS-PAGE.
Amino Acid Sequence:ADPQVQVVTQ DEREQLYTPA SLKCSLQNAQ EALIVTWQKK KAVSPENMVT FSENHGVVIQ PAYKDKINIT QLGLQNSTIT FWNITLEDEG CYMCLFNTFG FGKISGTACL TVYVQPIVSL HYKFSEDHLN ITCSATARPA PMVFWKVPRS GIENSTVTLS HPNGTTSVTS ILHIKDPKNQ VGKEVICQVL HLGTVTDFKQ TVNKGLEPKS CDKTHTCPPC PAPELLGGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT KPREEQYNST YRVVSVLTVL HQDWLNGKEY KCKVSNKALP APIEKTISKA KGQPREPQVY TLPPSRDELT KNQVSLTCLV KGFYPSDIAV EWESNGQPEN NYKTTPPVLD SDGSFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK SLSLSPGKHH HHHH

CD200 is a type-1 membrane glycoprotein which is a part of the immunoglobulin superfamily due to its 2 immunoglobulin domains. CD200 regulates myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in various tissues. CD200 is also Costimulates T-cell proliferation.

CD200 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 444 amino acids (31-232a.a.) and having a molecular mass of 49.7kDa (Molecular size on SDS-PAGE will appear at approximately 57-70 kDa).CD200 is expressed with a 242 amino acid hIgG-His tag at C-Terminus and purified by proprietary chromatographic techniques.

UniProt Protein Function:Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.
NCBI Summary:This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
UniProt Code:P41217
NCBI GenInfo Identifier:311033489
NCBI Gene ID:4345
NCBI Accession:P41217.4
UniProt Secondary Accession:P41217,Q6J2Q6, Q6PIQ4, Q8TB85, Q9H3J3, B3KQI1, B4DLW9 D3DN65,
UniProt Related Accession:P41217
Molecular Weight:32,975 Da
NCBI Full Name:OX-2 membrane glycoprotein
NCBI Synonym Full Names:CD200 molecule
NCBI Official Symbol:CD200��
NCBI Official Synonym Symbols:MRC; MOX1; MOX2; OX-2��
NCBI Protein Information:OX-2 membrane glycoprotein
UniProt Protein Name:OX-2 membrane glycoprotein
UniProt Synonym Protein Names:CD_antigen: CD200
UniProt Gene Name:CD200��
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Additional Information

Product Type:
Recombinant Protein
Species:
Human
Uniprot:
P41217
Research Area:
CD Antigens
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