CD Antigens Recombinant Proteins

Human CD200 Recombinant Protein (RPPB3108)

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SKU:
RPPB3108
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
P41217
Research Area:
CD Antigens

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Human CD200 Recombinant Protein
Product Code:RPPB3108
Size:20µg
Species:Human
Target:CD200
Synonyms:MOX1, MOX2, MRC, OX-2, OX-2 membrane glycoprotein, CD_antigen, CD200.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:CD200 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSQVQVVTQ DEREQLYTPA SLKCSLQNAQ EALIVTWQKK KAVSPENMVT FSENHGVVIQ PAYKDKINIT QLGLQNSTIT FWNITLEDEG CYMCLFNTFG FGKISGTACL TVYVQPIVSL HYKFSEDHLN ITCSATARPA PMVFWKVPRS GIENSTVTLS HPNGTTSVTS ILHIKDPKNQ VGKEVICQVL HLGTVTDFKQ TVNKG

CD200 is a type-1 membrane glycoprotein which is a part of the immunoglobulin superfamily due to its 2 immunoglobulin domains. CD200 regulates myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in various tissues. CD200 is also Costimulates T-cell proliferation.

CD200 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 225 amino acids (31-232 a.a) and having a molecular mass of 24.8kDa. CD200 is fused to a 23 amino acid His-tag at N-terminus.

UniProt Protein Function:Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.
NCBI Summary:This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
UniProt Code:P41217
NCBI GenInfo Identifier:311033489
NCBI Gene ID:4345
NCBI Accession:P41217.4
UniProt Secondary Accession:P41217,Q6J2Q6, Q6PIQ4, Q8TB85, Q9H3J3, B3KQI1, B4DLW9 D3DN65,
UniProt Related Accession:P41217
Molecular Weight:32,975 Da
NCBI Full Name:OX-2 membrane glycoprotein
NCBI Synonym Full Names:CD200 molecule
NCBI Official Symbol:CD200��
NCBI Official Synonym Symbols:MRC; MOX1; MOX2; OX-2��
NCBI Protein Information:OX-2 membrane glycoprotein
UniProt Protein Name:OX-2 membrane glycoprotein
UniProt Synonym Protein Names:CD_antigen: CD200
UniProt Gene Name:CD200��
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