Immune Checkpoint Recombinant Proteins
Human CD162 Recombinant Protein (His Tag) (HDPT0084)
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- SKU:
- HDPT0084
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
Description
Human CD162 Recombinant Protein (His Tag)
| Description: | This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants. |
| Product name: | Human CD162 Recombinant Protein (His Tag) |
| Synonyms: | PSGL1,CD162,SELPLG,Selectin P ligand |
| Type: | protein |
| Size: | 50 µg |
| Name: | CD162 |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | Contact Technical Support |
| Purity: | > 95% |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | C- 6×His tag |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | CD162（Leu18-Cys320）+6×His tag |
| Gene ID: | 6404 |
| Uniprot: | Q14242 |
| Molecular Weight: | 31.4 kDa |
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