Human CD14 Monoclonal Antibody (APC Conjugated) [M5E2](AGEL2081)

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SKU:
AGEL2081
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC

Description

Antibody Name:Human CD14 Monoclonal Antibody (APC Conjugated)
Antibody Code:AGEL2081
Size:50 Tests
Clone:M5E2
Synonyms:Monocyte differentiation antigen CD14,CD14,Myeloid cell-specific leucine-rich glycoprotein
Host Species:Mouse
Species Reactivity:Human
Applications:FC
Concentration:5uL
Isotype:IgG2a,k
Conjugation:APC
Applications:FC
Recommended Dilution:Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Storage Buffer:PBS with 0.05% Proclin300, 1% BSA
Storage:Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.
Gene ID:929
Uniprot:P08571
Background:CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens, and in the upregulation of adhesion molecules and expression of cytokines in monocytes and neutrophils.
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