Human CD135 / Flt3 ELISA Kit

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SKU:
HUFI00368
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P36888
Sensitivity:
37.5pg/ml
Range:
62.5-4000pg/ml
ELISA Type:
Sandwich
Synonyms:
Flt3, FMS Like Tyrosine Kinase 3, CD135, Flk-2, STK-1, CD135, CD135 antigen, fetal liver kinase 2, FL cytokine receptor, FLK2, FLT-3, FLT3 receptor tyrosine kinase, Fms-like tyrosine kinase 3, fms-related tyrosine kinase 3, growth factor receptor tyr
Reactivity:
Human
Research Area:
Immunology

Description

Human CD135 / Flt3 ELISA Kit

CD135 / Flt3 encodes a class III receptor tyrosine kinase that regulates hematopoiesis. CD135 / Flt3 is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation and autophosphorylation of the receptor. CD135 / Flt3 activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations in CD135 / Flt3 result in acute myeloid leukemia and acute lymphoblastic leukemia.

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