Immune Checkpoint Recombinant Proteins

Human CD123 Recombinant Protein (hFc-His Tag) (HDPT0003)

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SKU:
HDPT0003
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immune Checkpoint

Description

Human CD123 Recombinant Protein (hFc-His Tag)

Description:Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells
Product name:Human CD123 Recombinant Protein (hFc-His Tag)
Synonyms:IL3R, IL3RA, IL-3Ra, IL-3R-alpha, IL3RAY, IL3RX, IL3RY, CD123 antigen, CD123, hIL3Ra, hIL-3Ra, MGC34174, IL-3 R alpha
Type:protein
Size:50 µg
Name:CD123
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:ELISA
Purity:> 95%
Purification:affinity purification
Format:Lyophilized
Conjugate:C-Human Fc and 6×His tag
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:CD123(Thr19-Arg305)+hFc(Glu99-Ala330)+6×His tag
Gene ID:3563
Uniprot:P26951
Molecular Weight:80-90 kDa
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