Description
Antibody Name: | Human CD11c Monoclonal Antibody (AF647 Conjugated) |
Antibody Code: | AGEL1464 |
Size: | 50 Tests |
Clone: | BU15 |
Synonyms: | Integrin alpha-X,Itgax,CD11 antigen-like family member C,Leukocyte adhesion receptor p150+95,CD11c |
Host Species: | Mouse |
Species Reactivity: | Human |
Applications: | FC |
Concentration: | 5uL |
Isotype: | IgG2a,k |
Conjugation: | AF647 |
Applications: | FC |
Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
Storage Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Storage: | Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. |
Gene ID: | 3687 |
Uniprot: | P20702 |
Background: | CD11c is a 145-150 kD type I transmembrane glycoprotein also known as integrin αX and CR4. CD11c non-covalently associates with integrin β2 (CD18) and is expressed on monocytes/macrophages, dendritic cells, granulocytes, NK cells, and subsets of T and B cells. CD11c has been reported to play a role in adhesion and CTL killing through its interactions with fibrinogen, CD54, and iC3b. |
Human peripheral blood monocytes are stained with Anrti-Human CD11c Monoclonal Antibody(AF647 Conjuaged)(filled gray histogram). Unstained monocytes (empty black histogram) are used as control. |