Immune Checkpoint Recombinant Proteins

Human CCR8 Recombinant Protein (hFc Tag) (HDPT0481)

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SKU:
HDPT0481
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immune Checkpoint

Description

Human CCR8 Recombinant Protein (hFc Tag)

Description:This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq, Jul 2008]
Product name:Human CCR8 Recombinant Protein (hFc Tag)
Synonyms:CC-CKR-8; CCR-8; CDw198; CKRL1; CMKBR8; CMKBRL2; CY6; GPRCY6; TER1
Type:protein
Size:50 µg
Name:CCR8
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:Contact Technical Support
Purity:Contact Technical Support
Purification:affinity purification
Format:Lyophilized
Conjugate:C-Human Fc
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:CCR8 (Met1-Lys35)+hFc(GLU99-ALA330)
Gene ID:
Uniprot:P51685
Molecular Weight:29.37 kDa
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