Human Cbl-c/CBL-3 Recombinant Protein (RPES3619)
- SKU:
- RPES3619
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
system_update_altDatasheet
Human Cbl-c/CBL-3 Recombinant Protein
CBL proteins, such as Cbl-c, are phosphorylated upon activation of a variety of receptors that signal via protein tyrosine kinases. Through interactions with proteins containing SRC homology-2 (SH2) and SH3 domains, CBL proteins modulate downstream cell signaling. Cbl-c is a member of the Cbl family of E3 ubiquitin ligases. Expression of Cbl-c gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for Cbl-c gene.
| Product Name: | Human Cbl-c/CBL-3 Recombinant Protein (RPES3619) |
| Product Code: | RPES3619 |
| Size: | 20µg |
| Species: | Human |
| Expressed Host: | Baculovirus-Insect Cells |
| Synonyms: | CBL-3,CBL-SL,RNF57 |
| Accession: | AAH28915.1 |
| Sequence: | Met 1-Ala474 |
| Fusion tag: | N-His & GST |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | A DNA sequence encoding the human CBLC (AAH28915.1) (Met1-Ala474) was expressed with the N-terminal polyhistidine-tagged GST tag at the N-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 80.2 kDa |
| AP Mol Mass: | 66 kDa |
| Formulation: | Lyophilized from sterile 20mM Tris, 500mM Nacl, 10% glycerol, pH 8.0 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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