Human CARHSP1 Recombinant Protein (RPPB2985)

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RPPB2985

Description

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Product Name:Human CARHSP1 Recombinant Protein
Product Code:RPPB2985
Size:10µg
Species:Human
Target:CARHSP1
Synonyms:Calcium-regulated heat stable protein 1, Calcium-regulated heat-stable protein of 24 kDa, CRHSP-24, CARHSP1, asCSDC1, MGC111446.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The CRAHSP1 solution (0.5 mg/ml) contains 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol and 0.1M NaCl.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MSSEPPPPPQ PPTHQASVGL LDTPRSRERS PSPLRGNVVP SPLPTRRTRT FSATVRASQG PVYKGVCKCF CRSKGHGFIT PADGGPDIFL HISDVEGEYV PVEGDEVTYK MCSIPPKNEK LQAVEVVITH LAPGTKHETW SGHVISS

CRAHSP1 is a serine phosphoprotein initially identified as a physiological substrate for the Ca2+-calmodulin regulated protein phosphatase calcineurin (PP2B). CRAHSP1 interacts with the STYX/dead phosphate protein in developing spermatids and is a paralog of the brain-specific mRNA-binding protein PIPPIN. It is believed to have a common role in calcium-mediated signal transduction resulting from phosphorylation on serine residues.

CRAHSP1 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 167 amino acids (1-147 a.a.) and having a molecular mass of 18kDa. The CRAHSP1 is purified by proprietary chromatographic techniques.

UniProt Protein Function:DIRAS1: Displays low GTPase activity and exist predominantly in the GTP-bound form. Belongs to the small GTPase superfamily. Di-Ras family.Protein type: G protein, monomeric, di-Ras; G protein; G protein, monomericChromosomal Location of Human Ortholog: 19p13.3Cellular Component: plasma membraneMolecular Function: GTP binding; GTPase activity; mitogen-activated protein kinase bindingBiological Process: positive regulation of MAP kinase activity
UniProt Protein Details:
NCBI Summary:DIRAS1 belongs to a distinct branch of the functionally diverse Ras (see HRAS; MIM 190020) superfamily of monomeric GTPases.[supplied by OMIM, Apr 2004]
UniProt Code:O95057
NCBI GenInfo Identifier:62286591
NCBI Gene ID:148252
NCBI Accession:O95057.1
UniProt Secondary Accession:O95057
UniProt Related Accession:O95057
Molecular Weight:22,329 Da
NCBI Full Name:GTP-binding protein Di-Ras1
NCBI Synonym Full Names:DIRAS family GTPase 1
NCBI Official Symbol:DIRAS1��
NCBI Official Synonym Symbols:RIG; GBTS1; Di-Ras1��
NCBI Protein Information:GTP-binding protein Di-Ras1
UniProt Protein Name:GTP-binding protein Di-Ras1
UniProt Synonym Protein Names:Distinct subgroup of the Ras family member 1; Ras-related inhibitor of cell growth; Rig; Small GTP-binding tumor suppressor 1
Protein Family:GTP-binding protein
UniProt Gene Name:DIRAS1��
UniProt Entry Name:DIRA1_HUMAN
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Additional Information

Product Type:
Recombinant Protein
Species:
Human
Uniprot:
O95057
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