Human CAPSL Recombinant Protein (RPPB2981)
- SKU:
- RPPB2981
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q8WWF8
Description
| Product Name: | Human CAPSL Recombinant Protein |
| Product Code: | RPPB2981 |
| Size: | 20µg |
| Species: | Human |
| Target: | CAPSL |
| Synonyms: | Calcyphosine-like protein, CAPSL, MGC26610. |
| Source: | Escherichia Coli |
| Physical Appearance: | CAPSL is supplied as a sterile filtered clear solution. |
| Formulation: | CAPSL protein at 1mg/ml in 20mM Tris-HCL, pH-8, 0.2M NaCl, 5mM DTT and 20% Glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MAGTARHDRE MAIQAKKKLT TATDPIERLR LQCLARGSAG IKGLGRVFRI MDDDNNRTLD FKEFMKGLND YAVVMEKEEV EELFQRFDKD GNGTIDFNEF LLTLRPPMSR ARKEVIMQAF RKLDKTGDGV ITIEDLREVY NAKHHPKYQN GEWSEEQVFR KFLDNFDSPY DKDGLVTPEE FMNYYAGVSA SIDTDVYFII MMRTAWKL |
CAPSL is a calcium-binding protein holding two conserved calcium-binding motifs (EF-hands) which are found in a superfamily of calcium sensors and calcium signal modulators. In addition, the CAPSL gene is in the same linkage disequilibrium (LD) block as the IL7R gene and there is well known association between the CAPSL-IL7R locus and type 1 diabetes.
CAPSL Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 228 amino acids (1-208) and having a molecular mass of 26.3 kDa.The CAPSL is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
| UniProt Protein Function: | CAPSL: Chromosomal Location of Human Ortholog: 5p13.2Cellular Component: cytoplasmMolecular Function: calcium ion binding |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8WWF8 |
| NCBI GenInfo Identifier: | 110835717 |
| NCBI Gene ID: | 133690 |
| NCBI Accession: | NP_653248.3 |
| UniProt Secondary Accession: | Q8WWF8 |
| UniProt Related Accession: | Q8WWF8 |
| Molecular Weight: | |
| NCBI Full Name: | calcyphosin-like protein |
| NCBI Synonym Full Names: | calcyphosine-like |
| NCBI Official Symbol: | CAPSL�� |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | calcyphosin-like protein |
| UniProt Protein Name: | Calcyphosin-like protein |
| UniProt Synonym Protein Names: | |
| Protein Family: | Calcyphosin-like protein |
| UniProt Gene Name: | CAPSL�� |
| UniProt Entry Name: | CAPSL_HUMAN |
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