Enzymes Recombinant Proteins
Human CAMK2N1 Recombinant Protein (RPPB2974)
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- SKU:
- RPPB2974
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q7Z7J9
- Research Area:
- Enzymes
Description
| Product Name: | Human CAMK2N1 Recombinant Protein |
| Product Code: | RPPB2974 |
| Size: | 10µg |
| Species: | Human |
| Target: | CAMK2N1 |
| Synonyms: | PRO1489; RP11-401M16.1, Calcium/calmodulin-dependent protein kinase II inhibitor 1, CaMKII inhibitory protein alpha, CaMKIIN-alpha, CAMK2N1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | CAMK2N1 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMSEVLPY GDEKLSPYGD GGDVGQIFSC RLQDTNNFFG AGQNKRPPKL GQIGRSKRVV IEDDRIDDVL KNMTDKAPPG V |
Calcium/Calmodulin Dependent Protein Kinase II Inhibitor 1 (CAMK2N1), which interacts with CAMK2B, is a part of the CAMK2N family. CAMK2N1 is also interacts with CAMK2A in a way which requires CAMK2A activation by Ca2+. CAMK2N1 is potent and specific inhibitor of CaM-kinase II (CAMK2).
CAMK2N1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 101 amino acids (1-78 a.a) and having a molecular mass of 10.9kDa. CAMK2N1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | CAMK2N1: Potent and specific inhibitor of CaM-kinase II (CAMK2). Belongs to the CAMK2N family.Protein type: Inhibitor; Protein kinase, regulatory subunitChromosomal Location of Human Ortholog: 1p36.12Cellular Component: postsynaptic membrane; cell soma; postsynaptic density; dendrite; cell junctionMolecular Function: calcium-dependent protein kinase inhibitor activity; protein kinase bindingBiological Process: negative regulation of protein kinase activity |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q7Z7J9 |
| NCBI GenInfo Identifier: | 74750243 |
| NCBI Gene ID: | 55450 |
| NCBI Accession: | Q7Z7J9.1 |
| UniProt Secondary Accession: | Q7Z7J9 |
| UniProt Related Accession: | Q7Z7J9 |
| Molecular Weight: | 8,553 Da |
| NCBI Full Name: | Calcium/calmodulin-dependent protein kinase II inhibitor 1 |
| NCBI Synonym Full Names: | calcium/calmodulin-dependent protein kinase II inhibitor 1 |
| NCBI Official Symbol: | CAMK2N1�� |
| NCBI Official Synonym Symbols: | PRO1489�� |
| NCBI Protein Information: | calcium/calmodulin-dependent protein kinase II inhibitor 1; CaMKIINalpha; caMKII inhibitory protein alpha; caMKIIN-alpha |
| UniProt Protein Name: | Calcium/calmodulin-dependent protein kinase II inhibitor 1 |
| UniProt Synonym Protein Names: | CaMKII inhibitory protein alpha; CaMKIIN-alpha |
| Protein Family: | Calcium/calmodulin-dependent protein kinase II inhibitor |
| UniProt Gene Name: | CAMK2N1�� |
| UniProt Entry Name: | CK2N1_HUMAN |
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