Human Calumenin Recombinant Protein (RPES5017)

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SKU:
RPES5017
Product Type:
Recombinant Protein
Species:
Human

Description

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Human Calumenin Recombinant Protein

Calumenin belongs to the CREC family. It contains 6 EF-hand domains. Calumenin is expressed in skeletal muscle (at protein level). Calumenin interacts with GGCX and RYR1 in the presence of calcium ions; but not in the presence of EDTA. Calumenin is Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. It seems to inhibit gamma-carboxylase GGCX. Calumenin also binds 7 calcium ions with a low affinity and may modulate calcium release from the sarcoplasmic reticulum.

Product Name:Human Calumenin Recombinant Protein (RPES5017)
Product Code:RPES5017
Size:20µg
Species:Human
Expressed Host:HEK293 Cells
Synonyms:Calumenin, Crocalbin, IEF SSP 9302, CALU
Accession:O43852-1
Sequence:Met 1-Arg311
Fusion tag:C-His
Endotoxin:<1.0 EU per µg of the protein as determined by the LAL method.
Protein Construction:A DNA sequence encoding the human CALU (O43852-1) (Met1-Arg311) was expressed with a polyhistidine tag at the C-terminus.
Purity:> 90 % as determined by reducing SDS-PAGE.
Mol Mass:35.9 kDa
AP Mol Mass:46-52 kDa
Formulation:Lyophilized from sterile PBS; pH 7.4
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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system_update_altDatasheetHuman Calumenin Recombinant Protein Calumenin is a secreted calcium-binding protein that belongs to the CREC family. Calumenin contains six EF-hand domains and is expres