Human CALR/Calreticulin Recombinant Protein (RPES3863)

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SKU:
RPES3863
Product Type:
Recombinant Protein
Species:
Human

Description

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Human CALR/Calreticulin Recombinant Protein

Calreticulin is a widely conserved chaperone protein that functions in several cellular activities, such as cell adhesion, and is found in the endoplasmic reticulum. Calreticulin/CRT helps to keep calcium homeostasis and protein folding quality in check. Calreticulin is also present in the nucleus, implying that it may be involved with transcription regulation. Abnormal increases in serum autoantibodies against calreticulin are associated with systemic lupus erythematosus. Calreticulin abnormalities have been associated with a range of tumours, including myeloproliferative neoplasms. CRT/Calreticulin is a protein that participates in the HIV life cycle and protein metabolism. Human CALR/Calreticulin Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.

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