Human CALML5/CLSP Recombinant Protein (RPES0731)
- SKU:
- RPES0731
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
Human CALML5/CLSP Recombinant Protein
Calmodulin-like protein 5, also known as Calmodulin-like skin protein, CALML5 and CLSP, is a protein which contains four EF-hand domains. CALML5 / CLSP is particularly abundant in the epidermis where its expression is directly related to keratinocyte differentiation.The expression is very low in lung. CALML5 / CLSP binds calcium. It may be involved in terminal differentiation of keratinocytes. Coxsackievirus and adenovirus receptor (CAR) is a member of the immunoglobulin (Ig) superfamily and a component of epithelial tight junction. CAR functions as a primary receptor for coxsackievirus B and adenovirus (Ad) infection. CALML5 / CLSP is closely related to CAR. The structure and dynamics of human calmodulin-like skin protein CALML5 / CLSP have been characterized by NMR spectroscopy. The mobility of CALML5 / CLSP has been found to be different for the N-terminal and C-terminal domains. The N-terminal domain is characterized by four stable helices, which experience large fluctuations. This is shown to be due to mutations in the hydrophobic core. The overall N-terminal domain behavior is similar both in the full-length protein and in the isolated domain.
| Product Name: | Human CALML5/CLSP Recombinant Protein (RPES0731) |
| Product Code: | RPES0731 |
| Size: | 20µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | CLSP |
| Accession: | AAH39172.1 |
| Sequence: | Met 1-Glu 146 |
| Fusion tag: | N-His & GST |
| Endotoxin: | Please contact us for more information. |
| Protein Construction: | A DNA sequence encoding the human CALML5 (AAH39172.1) (Met 1-Glu 146) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus. |
| Purity: | > 92 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 44.2 kDa |
| AP Mol Mass: | 43 kDa |
| Formulation: | Lyophilized from sterile 20mM Tris, 150mM NaCl, 1mM DTT, 0.5mM GSH, 10% glycerol, pH 7.8 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Related Products
Human Acrp30 Protein Recombinant Protein (RPPB5717)
Cytokines Recombinant Proteins
Human PIP Protein Recombinant Protein (RPPB0886)
Growth Factors & Cytokines Recombinant Proteins