Cadherin-11; also known as OSF-4; Osteoblast cadherin and CDH11; is a type II classical cadherin from the cadherin superfamily; integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherins interact with themselves in a homophilic manner in connecting cells; may thus contribute to the sorting of heterogeneous cell types. Cadherin-11 contains five cadherin domains and is mainly expressed in brain. Mature cadherin proteins consists of a large N-terminal extracellular domain; a single membrane-spanning domain; and a small; highly conserved C-terminal cytoplasmic domain. It is shown that cadherin-11 is a viable molecular target for therapeutic intervention in Glioblastoma multiforme.
Product Name:
Human Cadherin1/CDH11 Recombinant Protein (RPES3758)
Product Code:
RPES3758
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
Cadherin 11 Type 2 OB-cadherin (Osteoblast), Cadherin 11 Type 2 OB-Cadherin (Osteoblast) Isoform CRA_c, CDH11
Accession:
Q96CZ9
Sequence:
Phe23-Thr617
Fusion tag:
C-Fc-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Cadherin-11 is produced by our Mammalian expression system and the target gene encoding Phe23-Thr617 is expressed with a Fc; 6His tag at the C-terminus.
Purity:
> 90 % as determined by reducing SDS-PAGE.
Mol Mass:
93.5 kDa
AP Mol Mass:
110 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS; pH 7.4 .
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
system_update_altDatasheetHuman Cadherin1/CDH11 Recombinant Protein Cadherin-11 is a type II classical cadherin member of the cadherin superfamily of integral membrane proteins that mediate calci
Human CSF2 Recombinant Protein (RPES5328)The product page for this antibody is being prepared. If you have a question please don't hesitate to get in touch!