Cell Biology Recombinant Proteins
Human Cadherin-3/CDH3 Recombinant Protein (RPES3822)
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- SKU:
- RPES3822
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Cell Biology
Description
system_update_altDatasheet
Human Cadherin-3/CDH3 Recombinant Protein
Cadherin-3 (CDH3) is a single-pass type I membrane protein that belongs to the cadherin superfamily. CDH3 is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. CDH3 is expressed in some normal epithelial tissues and in some carcinoma cell lines. CDH3 preferentially interacts with themselves in a homophilic manner in connecting cells. CDH3 is involved in loss of heterozygosity events in breast and prostate cancer. Mutations in CDH3 have been associated with congential hypotrichosis with juvenile macular dystrophy.
| Product Name: | Human Cadherin-3/CDH3 Recombinant Protein (RPES3822) |
| Product Code: | RPES3822 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Cadherin-3, Placental Cadherin, P-Cadherin, CDH3, CDHP |
| Accession: | P22223 |
| Sequence: | Glu25-Gly654 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Cadherin-3 is produced by our Mammalian expression system and the target gene encoding Glu25-Gly654 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 85 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 70.4 kDa |
| AP Mol Mass: | 88-110 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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