Human Cadherin-11 ELISA Kit

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SKU:
HUFI00901
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P55287
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
CDH11, Cadherin-11, CDHOB, OB-Cadherin, CAD11, OSF-4, OB, Osteoblast cadherin
Reactivity:
Human
Research Area:
Cell Biology

Description

Human Cadherin-11 ELISA Kit

Cadherin-11 is a type II classical cadherin from the cadherin superfamily, and is a integral membrane protein that regulate cell-cell adhesion via calcium.Mature cadherin proteins are made up of a large N-terminal extracellular domain, a single membrane-spanning domain, and a tiny, highly conserved C-terminal cytoplasmic domain. The upregulation of this cadherin in osteoblastic cell lines and its expression in bone formation and maintenance suggest a particular function in bone development and evolution. CDH11 is involved in the development of several nervous system disorders, including Elsahy-Waters Syndrome and Aneurysmal Bone Cysts. WNT Signaling and Cell junction organization are two pathways that are linked to CDH11.

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