Human CABP7 Recombinant Protein (RPPB2958)

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RPPB2958

Description

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Product Name:Human CABP7 Recombinant Protein
Product Code:RPPB2958
Size:5µg
Species:Human
Target:CABP7
Synonyms:Calcium-binding protein 7, CaBP7, Calneuron II, Calneuron-2, CABP7, CALN2.
Source:Escherichia Coli
Physical Appearance:Sterile filtered colorless solution.
Formulation:CABP7 protein solution (0.5mg/ml) containing Phosphate-buffered saline (pH 7.4).
Stability:CABP7 Human Recombinant although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.
Purity:Greater than 80.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MPFHPVTAAL MYRGIYTVPN LLSEQRPVDI PEDELEEIRE AFKVFDRDGN GFISKQELGT AMRSLGYMPN EVELEVIIQR LDMDGDGQVD FEEFVTLLGP KLSTSGIPEK FHGTDFDTVF WKCDMQKLTV DELKRLLYDT FCEHLSMKDI ENIIMTEEES HLGTAEECPV DVETCSNQQI RQTCVRKS

Calcium-binding protein 7 (CABP7) contains 2 EF-hand domains. CABP7 negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. The CaBP family of EF-hand containing small Ca (2+)-binding proteins has lately emerged as significant regulators of multiple targets essential to normal neuronal function in the mammalian central nervous system.

CABP7 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 208 amino acids (1-188 a.a.) and having a molecular mass of 23.7kDa.CABP7 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:CABP7: Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity.
UniProt Protein Details:

Protein type:Membrane protein, integral

Chromosomal Location of Human Ortholog: 22q12.2

Cellular Component: perinuclear region of cytoplasm; integral to membrane; plasma membrane; trans-Golgi network membrane

Molecular Function:calcium ion binding

UniProt Code:Q86V35
NCBI GenInfo Identifier:32698884
NCBI Gene ID:164633
NCBI Accession:NP_872333
UniProt Related Accession:Q86V35
Molecular Weight:24,453 Da
NCBI Full Name:calcium-binding protein 7
NCBI Synonym Full Names:calcium binding protein 7
NCBI Official Symbol:CABP7��
NCBI Official Synonym Symbols:CALN2��
NCBI Protein Information:calcium-binding protein 7; calneuron 2; calneuron-2; calneuron II
UniProt Protein Name:Calcium-binding protein 7
UniProt Synonym Protein Names:Calneuron II; Calneuron-2
Protein Family:Calcium-binding protein
UniProt Gene Name:CABP7��
UniProt Entry Name:CABP7_HUMAN
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Additional Information

Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q86V35
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