Human C16ORF53 Recombinant Protein (RPPB2931)

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SKU:
RPPB2931
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q9BTK6

Description

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Product Name:Human C16ORF53 Recombinant Protein
Product Code:RPPB2931
Size:20µg
Species:Human
Target:C16ORF53
Synonyms:PAXIP1-associated protein 1, PTIP-associated protein 1, PA1, C16orf53, GAS.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:C16ORF53 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 10% glycerol, 2mM DTT and 0.1M NaCl.
Stability:C16ORF53 Human Recombinant although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.
Purity:Greater than 85.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MSLARGHGDT AASTAAPLSE EGEVTSGLQA LAVEDTGGPS ASAGKAEDEG EGGREETERE GSGGEEAQGE VPSAGGEEPA EEDSEDWCVP CSDEEVELPA DGQPWMPPPS EIQRLYELLA AHGTLELQAE ILPRRPPTPE AQSEEERSDE EPEAKEEEEE KPHMPTEFDF DDEPVTPKDS LIDRRRTPGS SARSQKREAR LDKVLSDMKR HKKLEEQILR TGRDLFSLDS EDPSPASPPL RSSGSSLFPR QRKY
UniProt Code:Q9BTK6

C16ORF53 is a component of a Set1-like multiprotein histone methyltransferase complex. C16ORF53 interacts with PAXIP1/PTIP; this interaction is direct and is necessary for the association with the rest of the PTIP complex. The C16ORF53 protein has a crucial role in maintaining genome stability, condensation of chromatin and progression through mitosis.

C16ORF53 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 274 amino acids (1-254 a.a.) and having a molecular mass of 29.9kDa (Molecular weight on SDS-PAGE will appear higher).C16ORF53 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

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