Human C10ORF54 Recombinant Protein (RPPB2924)
- SKU:
- RPPB2924
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9H7M9
Description
| Product Name: | Human C10ORF54 Recombinant Protein |
| Product Code: | RPPB2924 |
| Size: | 10µg |
| Species: | Human |
| Target: | C10ORF54 |
| Synonyms: | C10orf54, Chromosome 10 Open ReadingFrame 54, V-Domain Ig Suppressor Of T Cell Activation, Stress-Induced Secreted Protein-1, Sisp-1, SISP1, Stress Induced Secreted Protein 1, Death Domain1alpha, DD1alpha, PP2135, B7-H5, VISTA,B7H5, GI24. |
| Source: | Sf9 Insect cells |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | C10ORF54 protein solution (0.5mg/ml) containing PhosphateBuffered Saline (pH 7.4) and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greaterthan 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | FKVATPYSLYVCPEGQNVTL TCRLLGPVDK GHDVTFYKTW YRSSRGEVQT CSERRPIRNL TFQDLHLHHG GHQAANTSHDLAQRHGLESA SDHHGNFSIT MRNLTLLDSG LYCCLVVEIR HHHSEHRVHG AMELQVQTGK DAPSNCVVYPSSSQDSENIT AAVEHHHHHH |
Chromosome 10 Open Reading Frame 54, also known as C10ORF54 is part ofthe immunoglobulin superfamily. Like a transmembrane molecule, C10ORF54 isexpressed in the bone on embryonic stem cells (ESCs), and on tumor cell surface as well. Accordingly, C10ORF54 supports the differentiation ofESC and ehhances BMP4 induced signaling in ESC, however C10ORF54 is also downregulated following to BMP4 exposure.
C10ORF54 Human Recombinant produced in Sf9 Baculoviruscells is a single, glycosylated polypeptide chain containing 170 amino acids (33-194a.a) and having a molecular mass of 19.1kDa. (Migrates at 28-40kDa on SDS-PAGEunder reducing conditions). C10ORF54 is fused to an 8 amino acid His-tag at C-terminus& purified by proprietary chromatographic techniques.
| UniProt Protein Function: | VISTA: May stimulate MMP14-mediated MMP2 activation |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 10q22.1 Cellular Component: cell surface; intercellular junction; plasma membrane Biological Process: cell-cell adhesion |
| UniProt Code: | Q9H7M9 |
| NCBI GenInfo Identifier: | 62339432 |
| NCBI Gene ID: | 64115 |
| NCBI Accession: | NP_071436.1 |
| UniProt Related Accession: | Q9H7M9 |
| Molecular Weight: | 34kDa |
| NCBI Full Name: | V-type immunoglobulin domain-containing suppressor of T-cell activation |
| NCBI Synonym Full Names: | V-set immunoregulatory receptor |
| NCBI Official Symbol: | VSIR�� |
| NCBI Official Synonym Symbols: | B7H5; GI24; B7-H5; Dies1; PD-1H; SISP1; VISTA; PP2135; C10orf54; DD1alpha�� |
| NCBI Protein Information: | V-type immunoglobulin domain-containing suppressor of T-cell activation |
| UniProt Protein Name: | V-type immunoglobulin domain-containing suppressor of T-cell activation |
| UniProt Synonym Protein Names: | Platelet receptor Gi24 |
| UniProt Gene Name: | C10orf54�� |
| UniProt Entry Name: | VISTA_HUMAN |
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