Human c-Src / CSK / Tyrosine-protein kinase ELISA Kit

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SKU:
HUFI01100
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P41240
Sensitivity:
0.469ng/ml
Range:
0.781-50ng/ml
ELISA Type:
Sandwich
Synonyms:
CSK, C-Src kinase, Protein-tyrosine kinase CYL
Reactivity:
Human
Research Area:
Immunology

Description

Human c-Src / CSK / Tyrosine-protein kinase ELISA Kit

c-Src/CSK/Tyrosine-protein kinase is involved in a variety of processes, including the regulation of Src family kinases. Through its interaction with the protein encoded by the protein tyrosine phosphatase, non-receptor type 22 (PTPN22) gene, it plays an important role in T-cell activation. c-Src/CSK/Tyrosine-protein kinase also phosphorylates C-terminal tyrosine residues on a variety of substrates, including the non-receptor tyrosine kinase protein encoded by the SRC proto-oncogene. The kinase activity of the Src family tyrosine kinases is suppressed by phosphorylation. This gene has an intronic polymorphism (rs34933034) that affects B-cell activation and is linked to systemic lupus erythematosus (SLE). Osteopetrosis and Lupus Erythematosus are two diseases linked to CSK.

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