Human BUD31 Recombinant Protein (RPPB2918)
- SKU:
- RPPB2918
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P41223
Description
| Product Name: | Human BUD31 Recombinant Protein |
| Product Code: | RPPB2918 |
| Size: | 10µg |
| Species: | Human |
| Target: | BUD31 |
| Synonyms: | BUD31 homolog (S. cerevisiae), Cwc14, EDG-2, EDG2, fSAP17, G10, YCR063W, Protein G10 homolog. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | BUD31 protein solution (0.25mg/ml) contains 20mM Tris-HCl buffer, (pH 8.0), 0.2M NaCl, 40% glycerol and 2mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMPKVKRS RKAPPDGWEL IEPTLDELDQ KMREAETEPH EGKRKVESLW PIFRIHHQKT RYIFDLFYKR KAISRELYEY CIKEGYADKN LIAKWKKQGY ENLCCLRCIQ TRDTNFGTNC ICRVPKSKLE VGRIIECTHC GCRGCSG |
BUD31 is a member of the BUD31 (G10) family. BUD31 is a nuclear protein which contains a putative nuclear translocation sequence, an N-terminal acidic domain and a cysteine-rich C-terminal domain containing a putative Zinc-finger structure. Based on the structure of BUD31 it is suggested that BUD31 might be a nuclear regulator of transcription.
BUD31 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 167 amino acids (1-144 a.a.) and having a molecular mass of 19.4kDa.BUD31 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | BUD31: Belongs to the BUD31 (G10) family. |
| UniProt Protein Details: | Protein type:Spliceosome; Transcription factor Chromosomal Location of Human Ortholog: 7q22.1 Cellular Component: nuclear chromatin; nucleoplasm; nucleus; spliceosome Molecular Function:ligand-dependent nuclear receptor transcription coactivator activity; nuclear hormone receptor binding; protein binding; transcription factor activity Biological Process: nuclear mRNA splicing, via spliceosome; regulation of transcription from RNA polymerase II promoter |
| UniProt Code: | P41223 |
| NCBI GenInfo Identifier: | 23831082 |
| NCBI Gene ID: | 8896 |
| NCBI Accession: | P41223.2 |
| UniProt Secondary Accession: | P41223,Q6IB53, Q9UDV1, A4D274, B7Z4S9, D6W5S6, |
| UniProt Related Accession: | P41223 |
| Molecular Weight: | 17kDa |
| NCBI Full Name: | Protein BUD31 homolog |
| NCBI Synonym Full Names: | BUD31 homolog |
| NCBI Official Symbol: | BUD31�� |
| NCBI Official Synonym Symbols: | G10; EDG2; Cwc14; EDG-2; fSAP17; YCR063W�� |
| NCBI Protein Information: | protein BUD31 homolog |
| UniProt Protein Name: | Protein BUD31 homolog |
| UniProt Synonym Protein Names: | Protein EDG-2; Protein G10 homolog |
| Protein Family: | Protein |
| UniProt Gene Name: | BUD31�� |
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