Human BST1 / Bone Marrow Stromal Cell Antigen 1 ELISA Kit

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SKU:
HUFI01804
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q10588
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
BST1, CD157, ADP-ribosyl cyclase 2, Cyclic ADP-ribose hydrolase 2, BP-3, BST1, cADPr hydrolase 2, CD157, ADP-ribosyl cyclase 2, Bone marrow stromal antigen 1, bone marrow stromal cell antigen 1, BST-1, cADPr hydrolase 2, CD157, CD157 antigen, Cyclic
Reactivity:
Human
Research Area:
Cell Biology

Description

Human BST1 / Bone Marrow Stromal Cell Antigen 1 ELISA

BST1 is a glycosylphosphatidylinositol-anchored molecule produced by bone marrow stromal cells that aids in the development of pre-B cells. BST1 expression is more frequent in rheumatoid arthritis bone marrow stromal cell lines. BST1 overexpression in the stromal cell population may play a role in the polyclonal B-cell abnormalities observed in rheumatoid arthritis. Paroxysmal Nocturnal Hemoglobinuria and Hemoglobinuria are two other diseases linked to BST1. Protein metabolism, as well as post-translational modification - synthesis of GPI-anchored proteins, are among the mechanisms affected by BST1.

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