Cytokines Recombinant Proteins

Human BMP 7 Recombinant Protein (RPPB0102)

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SKU:
RPPB0102
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
P18075
Research Area:
Cytokines

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Human BMP 7 Recombinant Protein
Product Code:RPPB0102
Size:50µg
Species:Human
Target:BMP 7
Synonyms:Osteogenic Protein 1, OP-1, BMP-7, Bone morphogenetic protein 7, BMP7, OP1.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:BMP-7 protein (0.5mg/ml) solution contains 10mM sodium citrate pH3.5 and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
Purity:Greater than 95.0% as determined by SDS-PAGE.
Amino Acid Sequence:MSTGSKQRSQ NRSKTPKNQE ALRMANVAEN SSSDQRQACK KHELYVSFRD LGWQDWIIAP EGYAAYYCEG ECAFPLNSYM NATNHAIVQTLVHFINPETV PKPCCAPTQL NAISVLYFDD SSNVILKKYR NMVVRACGCH LEHHHHHH

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.

BMP7 Human Recombinant produced in E.Coli is a monomeric, non-glycosylated, polypeptide chain containing 148 amino acids (293-431) and having a molecular mass of 16.8 kDa. The BMP-7 is fused to 8 amino acid His Tag at C-terminus & purified by proprietary chromatographic techniques.

UniProt Code:P18075
NCBI GenInfo Identifier:115078
NCBI Gene ID:655
NCBI Accession:P18075.1
UniProt Secondary Accession:P18075,Q9H512, Q9NTQ7,
UniProt Related Accession:P18075
Molecular Weight:431
NCBI Full Name:Bone morphogenetic protein 7
NCBI Synonym Full Names:bone morphogenetic protein 7
NCBI Official Symbol:BMP7��
NCBI Official Synonym Symbols:OP-1��
NCBI Protein Information:bone morphogenetic protein 7; osteogenic protein 1
UniProt Protein Name:Bone morphogenetic protein 7
UniProt Synonym Protein Names:Osteogenic protein 1; OP-1; INN: Eptotermin alfa
Protein Family:Bone morphogenetic protein
UniProt Gene Name:BMP7��
UniProt Entry Name:BMP7_HUMAN
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