Cytokines Recombinant Proteins

Human BMP 7 Recombinant Protein (RPPB0101)

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SKU:
RPPB0101
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
P18075
Research Area:
Cytokines

Description

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Product Name:Human BMP 7 Recombinant Protein
Product Code:RPPB0101
Size:10µg
Species:Human
Target:BMP 7
Synonyms:Osteogenic Protein 1, BMP-7.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation:BMP-7 was lyophilized from a concentrated (1mg/ml) sterile solution containing 10mM sodium citrate pH=3.5.
Solubility:It is recommended to briefly centrifuge the vial prior to opening to bring the contents to the bottom. Reconstitute in 20mM-100mM acetic acid at a concentration of 0.1-0.5mg per ml. Stock solutions should be apportioned into working aliquots and stored at <-20�C. Further dilutions should be made in appropriate buffered solutions.
Stability:Lyophilized BMP-7 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BMP 7 Human should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Purity:Greater than 95.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Amino Acid Sequence:The sequence of the first five N-terminal amino acids was determined and was found to be Ser-Thr-Gly-Ser-Lys

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.

Bone Morphogenetic Protein-7 Human Recombinant produced in E.Coli is a monomeric, non-glycosylated, polypeptide chain containing 139 amino acids and having a molecular mass of 15679.97 Dalton. The BMP-7 is purified by proprietary chromatographic techniques.

UniProt Code:P18075
NCBI GenInfo Identifier:115078
NCBI Gene ID:655
NCBI Accession:P18075.1
UniProt Secondary Accession:P18075,Q9H512, Q9NTQ7,
UniProt Related Accession:P18075
Molecular Weight:431
NCBI Full Name:Bone morphogenetic protein 7
NCBI Synonym Full Names:bone morphogenetic protein 7
NCBI Official Symbol:BMP7��
NCBI Official Synonym Symbols:OP-1��
NCBI Protein Information:bone morphogenetic protein 7; osteogenic protein 1
UniProt Protein Name:Bone morphogenetic protein 7
UniProt Synonym Protein Names:Osteogenic protein 1; OP-1; INN: Eptotermin alfa
Protein Family:Bone morphogenetic protein
UniProt Gene Name:BMP7��
UniProt Entry Name:BMP7_HUMAN
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