Human BDKRB2 Full-Length Bioactive Membrane Protein (HDFP104)

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SKU:
HDFP104
Product Type:
Recombinant Protein
Protein Type:
Full-Length Bioactive Membrane Protein
Species:
Human
Uniprot:
P30411

Description

system_update_altDatasheet
Product nameHuman BDKRB2 full length protein-synthetic nanodisc
Size:10ug
Product SKU:HDFP104
Product CategoryFull Length Transmembrane Proteins
Target:BDKRB2
Uniprot:P30411
Description:Human BDKRB2 full length protein-synthetic nanodisc
Molecular Weight:The human full length BDKRB2 protein has a MW of 44.5 kDa
Protein Family:Druggable Genome, GPCR, Transmembrane
Protein Pathways:Calcium signaling pathway, Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Regulation of actin cytoskeleton
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Synonyms:B2R; BK-2; BK2; BKR2; BRB2
Expression System:HEK293
Formulation:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Background:This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. Bradykinin is released upon activation by pathophysiologic conditions such as trauma and inflammation, and binds to its kinin receptors, B1 and B2. The B2 receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. [provided by RefSeq, Apr 2020]
Delivery:3-4 weeks
UsageResearch use only
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