Epigenetics & Nuclear Signaling Recombinant Proteins
Human BCAS2/DAM1 Recombinant Protein (RPES3343)
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- SKU:
- RPES3343
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Epigenetics & Nuclear Signaling
Description
system_update_altDatasheet
Human BCAS2/DAM1 Recombinant Protein
Breast Carcinoma-Amplified Sequence 2 (BCAS2) is a member of the SPF27 family. BCAS2 is a nuclear protein and widely expressed in many rtissues. BCAS2 is identified as being overexpressed in various breast cancer cell lines. BCAS2 is a component of the spliceosome, taking part in the removal of introns from mRNA precursors. BCAS2 interacts with estrogen receptor alpha and beta, thyroid hormone receptor beta, peroxisome proliferator-activated receptor gamma. BCAS2 functions as an ER co-activator and is capable of enhancing ER-mediated transcription.
| Product Name: | Human BCAS2/DAM1 Recombinant Protein (RPES3343) |
| Product Code: | RPES3343 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Pre-mRNA-Splicing Factor SPF27, Breast Carcinoma-Amplified Sequence 2, DNA Amplified in Mammary Carcinoma 1 Protein, Spliceosome-Associated Protein SPF 27, BCAS2, DAM1 |
| Accession: | O75934 |
| Sequence: | Ala2-Phe225 |
| Fusion tag: | C-6His, N-T7 |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Breast Carcinoma-Amplified Sequence 2 is produced by our E.coli expression system and the target gene encoding Ala2-Phe225 is expressed with a T7 tag at the N-terminus, 6His tag at the C-terminus. |
| Purity: | > 90 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 28.6 kDa |
| AP Mol Mass: | 60 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM TrisHCl, 200mM NaCl, 2mM DTT, pH 8.0. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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