Immune Checkpoint Recombinant Proteins
Human B7-H3 Recombinant Protein (mFc-His Tag) (HDPT0012)
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- SKU:
- HDPT0012
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
Description
Human B7-H3 Recombinant Protein (mFc-His Tag)
| Description: | The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Product name: | Human B7-H3 Recombinant Protein (mFc-His Tag) |
| Synonyms: | B7-H3, CD276, B7 homolog 3 |
| Type: | protein |
| Size: | 50 µg |
| Name: | B7-H3 |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | ELISA |
| Purity: | > 95% |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | C-Mouse Fc and 6×His tag |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | B7-H3（Leu29-Pro245）+mFc（Pro99-Lys330）+6×His |
| Gene ID: | 80381 |
| Uniprot: | Q5ZPR3 |
| Molecular Weight: | 70-75 kDa |
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