Immune Checkpoint Recombinant Proteins
Human B7-H2 Recombinant Protein (mFc-His Tag) (HDPT0029)
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- SKU:
- HDPT0029
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
Description
Human B7-H2 Recombinant Protein (mFc-His Tag)
| Description: | Inducible co-stimulator ligand (ICOSL), also known as B7-H2, is a member of the B7 family of co-stimulatory molecules related to B7-1 and B7-2.The protein is the ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function |
| Product name: | Human B7-H2 Recombinant Protein (mFc-His Tag) |
| Synonyms: | ICOSLG, B7-H2, B7H2, B7RP-1, B7RP1, CD275, GL50, ICOS-L, ICOSL, LICOS, ICOS ligand |
| Type: | protein |
| Size: | 50 µg |
| Name: | B7-H2 |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | Flow Cyt |
| Purity: | > 95% |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | C-Mouse Fc and 6×His tag |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | B7H2（Asp19-Thr256）+mFc（Pro99-Lys330）+6×His tag |
| Gene ID: | 23308 |
| Uniprot: | O75144 |
| Molecular Weight: | 53.9 kDa |
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