Immune Checkpoint Recombinant Proteins
Human B7-2 Recombinant Protein (mFc-His Tag) (HDPT0034)
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- SKU:
- HDPT0034
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
Description
Human B7-2 Recombinant Protein (mFc-His Tag)
| Description: | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. |
| Product name: | Human B7-2 Recombinant Protein (mFc-His Tag) |
| Synonyms: | CD86, B7-2, B70, CD28LG2, LAB72, MGC34413 |
| Type: | protein |
| Size: | 50 µg |
| Name: | B7-2 |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | Contact Technical Support |
| Purity: | > 95% |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | C-Mouse Fc and 6×His tag |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | B7-2（Leu26-Pro247）+mFc（Pro99-Lys330）+6×His tag |
| Gene ID: | 942 |
| Uniprot: | P42081 |
| Molecular Weight: | 52.4 kDa |
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