Immune Checkpoint Recombinant Proteins

Human B7-2 Recombinant Protein (hFc Tag) (HDPT0086)

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SKU:
HDPT0086
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immune Checkpoint

Description

Human B7-2 Recombinant Protein (hFc Tag)

Description:This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
Product name:Human B7-2 Recombinant Protein (hFc Tag)
Synonyms:CD86, B7-2, B70, CD28LG2, LAB72, MGC34413
Type:protein
Size:50 µg
Name:B7-2
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:ELISA, Flow Cyt
Purity:> 95%
Purification:affinity purification
Format:Lyophilized
Conjugate:C-Human Fc tag
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:B7-2(Leu26-Pro247)+hFc(Glu99-Ala330)
Gene ID:942
Uniprot:P42081
Molecular Weight:51.5 kDa
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