Human B3GNT2 Recombinant Protein (RPES1384)

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SKU:
RPES1384
Product Type:
Recombinant Protein
Species:
Human

Description

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Human B3GNT2 Recombinant Protein

B3GNT2 belongs to the beta-1,3-N-acetylglucosaminyltransferase family. It is a type II transmembrane protein which prefers the substrate of lacto-N-neotetraose. Alternative splicing produced 2 isoforms of the human protein. B3GNT2 catalyzes the initiation and elongation of poly-N- acetyllactosamine chains. Enzymatic activities of some glycosyltransferases are markedly increased via complex formation with other transferases or cofactor proteins. B3GNT2 and beta3Gn-T8 can form a heterodimer in vitro and that the complex exhibits much higher enzymatic activity than either enzyme alone. It is found that up-regulation of beta3Gn-T8 in differentiated HL-60 cells may increases poly-N-acetyllactosamine chains by activating intrinsic B3GNT2.

Product Name:Human B3GNT2 Recombinant Protein (RPES1384)
Product Code:RPES1384
Size:20µg
Species:Human
Expressed Host:HEK293 Cells
Synonyms:B3GN-T2,B3GNT,B3GNT-2,B3GNT1,BETA3GNT,BGnT-2,BGNT2
Accession:Q9NY97-1
Sequence:Lys29-Cys397
Fusion tag:N-Fc
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:A DNA sequence encoding the human B3GNT2 (Q9NY97-1) (Lys29-Cys397) was expressed,with the fused Fc region of human IgG1 at the N-terminus.
Purity:> 90 % as determined by reducing SDS-PAGE.
Mol Mass:71.2 kDa
AP Mol Mass:112-120 kDa
Formulation:Lyophilized from sterile PBS, pH 7.4
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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