Human ATG5 Recombinant Protein (RPPB5845)

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SKU:
RPPB5845
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q9H1Y0

Description

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Product Name:Human ATG5 Recombinant Protein
Product Code:RPPB5845
Size:10µg
Species:Human
Target:ATG5
Synonyms:Autophagy protein 5, APG5-like, Apoptosis-specific protein, ATG5, ASP, APG5, APG5L, hAPG5.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:ATG5 at a concentration of 0.25mg/ml containing 20mM Tris-HCl, pH 8.0, 1mM DTT , 0.2M NaCl and 40% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 85.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MTDDKDVLRD VWFGRIPTCF TLYQDEITER EAEPYYLLLPRVSYLTLVTD KVKKHFQKVM RQEDISEIWF EYEGTPLKWH YPIGLLFDLL ASSSALPWNITVHFKSFPEK DLLHCPSKDA IEAHFMSCMK EADALKHKSQ VINEMQKKDH KQLWMGLQND RFDQFWAINR KLMEYPAEEN GFRYIPFRIY QTTTERPFIQ KLFRPVAADG QLHTLGDLLKEVCPSAIDPE DGEKKNQVMI HGIEPMLETP LQWLSEHLSY PDNFLHISII PQPTD

ATG5 is a member of the autophagy-related (ATG) genes family. Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents. ATG5 protein is essential for autophagy. It conjugates to ATG12 and associates with isolation membrane to form autophagosomes. In addition ATG5 takes a vital part in the apoptotic process and it is expressed relatively late in the apoptotic process, downstream of caspase activity.

ATG5 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 295 amino acids (1-275a.a.) and having a molecular mass of 34.6kDa.ATG5 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Code:Q9H1Y0
NCBI GenInfo Identifier:17366828
NCBI Gene ID:9474
NCBI Accession:Q9H1Y0.2
UniProt Secondary Accession:Q9H1Y0,O60875, Q5JVR2, Q68DI4, Q9H2B8, Q9HCZ7,
UniProt Related Accession:Q9H1Y0
Molecular Weight:275
NCBI Full Name:Autophagy protein 5
NCBI Synonym Full Names:autophagy related 5
NCBI Official Symbol:ATG5��
NCBI Official Synonym Symbols:ASP; APG5; APG5L; hAPG5; APG5-LIKE��
NCBI Protein Information:autophagy protein 5; apoptosis-specific protein; ATG5 autophagy related 5 homolog
UniProt Protein Name:Autophagy protein 5
UniProt Synonym Protein Names:APG5-like; Apoptosis-specific protein
Protein Family:Autophagy protein
UniProt Gene Name:ATG5��
UniProt Entry Name:ATG5_HUMAN
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