Autophagy Recombinant Proteins

Human ATG4A Recombinant Protein (RPES3144)

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SKU:
RPES3144
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Autophagy

Description

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Human ATG4A Recombinant Protein

Cysteine Protease ATG4A (ATG4A) is a cytoplasmic protein that belongs to the peptidase C54 family. ATG4A is widely expressed in many tissues at a low level, but the highest expression is observed in skeletal muscle and brain. ATG4A is a cysteine protease required for autophagy; it cleaves the C-terminal part of MAP1LC3, GABARAPL2 or GABARAP. ATG4A is inhibited by N-ethylmaleimide. It is suggested that ATG4A has a significant role in suppressing various cancers.

Product Name:Human ATG4A Recombinant Protein (RPES3144)
Product Code:RPES3144
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Cysteine Protease ATG4A, AUT-Like 2 Cysteine Endopeptidase, Autophagin-2, Autophagy-Related Cysteine Endopeptidase 2, Autophagy-Related Protein 4 Homolog A, hAPG4A, ATG4A, APG4A, AUTL2
Accession:Q8WYN0
Sequence:Met 1-Val398
Fusion tag:N-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Autophagy Related 4 Homolog A is produced by our E.coli expression system and the target gene encoding Met1-Val398 is expressed with a 6His tag at the N-terminus.
Purity:> 85 % as determined by reducing SDS-PAGE.
Mol Mass:47.5 kDa
AP Mol Mass:45-55 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM PB, 150mM NaCl?pH7.4.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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