Autophagy Recombinant Proteins
Human ATG3 Recombinant Protein (RPES3124)
- SKU:
- RPES3124
Description
Human ATG3 Recombinant Protein
ATG3 (Ubiquitin-like-conjugating enzyme ATG3), also known as Apg3L and Apg3p, is a regulatory component of autophagosome biogenesis required for autophagy. ATG3 exhibits 98% aa sequence identity with both its mouse and rat orthologs. It is highly concentrated in the heart, skeletal muscle, kidneys, livers tissues, and placenta. As an E2-like enzyme, involves in autophagy and mitochondrial homeostasis. ATG8-like proteins are conjugated to PE by ATG3, which is required for autophagy. ATG3 can also act as a substrate for the conjugation of ATG12 to itself, which is required for mitochondrial homeostasis but not autophagy. Human ATG3 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
| Product Name: | Human ATG3 Recombinant Protein (RPES3124) |
| Product Code: | RPES3124 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Ubiquitin-like-conjugating enzyme ATG3, Autophagy-related protein 3, APG3-like, hApg3, Protein PC3-96, ATG3, APG3, APG3L |
| Accession: | Q9NT62 |
| Sequence: | Met 1-Met314 |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Ubiquitin-like-conjugating Enzyme ATG3/ATG3 is produced by our E.coli expression system and the target gene encoding Met1-Met314 is expressed. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 36 kDa |
| AP Mol Mass: | 38 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM TrisHCl,150mM NaCl,10% Glycerol,pH 8.0. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
Additional Information
Product Type: |
Recombinant Protein |
Species: |
Human |
Research Area: |
Autophagy |
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