Epigenetics & Nuclear Signaling Recombinant Proteins

Human ASF1A Recombinant Protein (RPES0825)

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SKU:
RPES0825
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Epigenetics & Nuclear Signaling

Description

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Human ASF1A Recombinant Protein

Human Histone Chaperone ASF1A (ASF1A) belongs to the H3/H4 family of histone chaperone proteins. ASF1A is ubiquitously expressed in many cells and tissues, interacting with histones H3 and H4. ASF1A cooperates with Chromatin Assembly Factor 1 to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. In addition, ASF1A is necessary for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.

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